教育经历

1982.09-1986.06  内蒙古民族大学，动物医学，专业学习，获学士学位

1986.09-1989.06  解放军农牧大学，病理学，专业学习，获硕士学位

1994.09-1997.06  第二军医大学，生理学，专业学习，获博士学位

工作经历

1989.09-1994.07  兰州军区后勤部军事医学研究所，助理研究员

1994.09-2003.07  第二军医大学，神经生物学教研室，讲师

2003.09-2011.07  上海体育学院，运动科学学院，副教授

2011.09-至今    37000cm威尼斯，运动科学学院，教授

研究方向

1.运动促进脑健康的分子机制

2.运动防治神经退行性疾病的分子机制

3.运动预防更年期后女性脑老化的分子机制

开授课程

运动心理学，运动生物化学，运动营养学，细胞生物学

科研项目

1.国家自然科学基金面上项目：乳酸/GPR81在运动促进小鼠突触可塑性中的作用及其机制（31971098），2020.01-2023.12, 58万，主持

2.国家自然科学基金面上项目：高脂饮食诱发肥胖损害大鼠学习记忆能力的内质网应激相关机制及有氧运动的调节作用（81572241），2016.01-2019.12，51万，主持

学术成果

1.Xue, X., Liu, B., Hu, J., Bian, X., & Lou, S.*(2022). The potential mechanisms of lactate in mediating exercise-enhanced cognitive function: A dual role as an energy supply substrate and a signaling molecule. Nutrition & Metabolism, 19(1), 52.

2.Feng, Y., Shi, R., Hu, J., & Lou, S.*(2022). Effects of neural-derived estradiol on actin polymerization and synaptic plasticity-related proteins in prefrontal and hippocampal cells of mice. Steroids, 177, 108935.

3.Feng, Y., Tian, X., Zhang, M., & Lou, S.*(2021). Treadmill exercise reverses the change of dendritic morphology and activates bndf-mtor signaling pathway in the hippocampus and cerebral cortex of ovariectomized mice. Journal of Molecular Neuroscience, 71(9), 1849–1862.

4.Xue, X., Li, F., Cai, M., Hu, J., Wang, Q., & Lou, S.*(2021). Interactions between endoplasmic reticulum stress and autophagy: Implications for apoptosis and neuroplasticity-related proteins in palmitic acid-treated prefrontal cells. Neural Plasticity, 2021, 8851327.

5.Hu, J., Cai, M., Shang, Q., Li, Z., Feng, Y., Liu, B., Xue, X., & Lou, S.* (2021). Elevated lactate by high-intensity interval training regulates the hippocampal BDNF expression and the mitochondrial quality control system. Frontiers in Physiology, 12, 629914.

6.沈晨菲, 娄淑杰*. (2021). 运动改善阿尔茨海默病的酮体相关机制研究进展. 中国细胞生物学学报, 43(1), 179-185.

7.商庆慧, 胡静芸, 李照润, & 娄淑杰*. (2021). SIRT1介导神经保护作用的研究进展. 生命的化学, 41(05), 931-937.

8.Cai, M.#, Hu, J.#, Liu, B., Li, J., Li, F., & Lou, S.* (2020). The molecular mechanisms of excessive hippocampal endoplasmic reticulum stress depressing cognition-related proteins expression and the regulatory effects of Nrf2. Neuroscience, 431, 152–165.

9.Hu, J., Cai, M., Liu, Y., Liu, B., Xue, X., Ji, R., Bian, X., & Lou, S.* (2020). The roles of GRP81 as a metabolic sensor and inflammatory mediator. Journal of Cellular Physiology, 235(12), 8938–8950.

10.Liu, B., Li, J., Lin, X., Hu, J., & Lou, S.* (2020). The metabolic changes in the hippocampus of an atherosclerotic rat model and the regulation of aerobic training. Metabolic Brain Disease, 35(6), 1017–1034.

11.卞学鹏, 姬瑞方, 刘蓓蓓, 胡静芸, 李明明, 薛香莉, & 娄淑杰*. (2020). 有氧运动降低胰岛素抵抗小鼠海马细胞焦亡相关蛋白及炎症因子的表达. 生理学报, 72(04), 455-462.

12.胡静芸, 蔡明, 商庆慧, 李照润, 娄淑杰*. (2020). 高强度间歇训练改善认知功能及其机制研究进展. 生理学报, 73(01), 126-136.

13.冯钰, 卞学鹏, 田旭, 商庆慧, 娄淑杰*. (2020). GPER在脑组织中作用及机制的研究进展. 生命科学, 33(01), 53-60.

14.王文家, 娄淑杰*. (2020). Sirt1对阿尔茨海默病氧化应激的调控和机制. 中国细胞生物学学报, 42(11), 136-142.

15.Li, J., Liu, Y., Liu, B., Li, F., Hu, J., Wang, Q., Li, M., & Lou, S.* (2019). Mechanisms of aerobic exercise upregulating the expression of hippocampal synaptic plasticity-associated proteins in diabetic rats. Neural Plasticity, 2019, 7920540.

16.Wang, Q., Hu, J., Liu, Y., Li, J., Liu, B., Li, M., & Lou, S.* (2019). Aerobic exercise improves synaptic-related proteins of diabetic rats by inhibiting FOXO1/NF-κB/NLRP3 inflammatory signaling pathway and ameliorating PI3K/Akt insulin signaling pathway. Journal of Molecular Neuroscience, 69(1), 28–38.

17.Li, J.*, Liu, B.*, Cai, M.*, Lin, X.*, & Lou, S.*(2019). Glucose metabolic alterations in hippocampus of diabetes mellitus rats and the regulation of aerobic exercise. Behavioural Brain Research, 364, 447–456.

18.李明明, 李静静, 刘蓓蓓, 杨亚南, 刘冬梅, & 娄淑杰*. (2019). mTOR在有氧运动调节胰岛素抵抗小鼠海马内突触可塑相关蛋白表达中的作用分析. 中国康复医学杂志, 34(03), 255-261.

19.Li, F., Liu, B., Cai, M., Li, J., & Lou, S.* (2018). Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise. Brain Research Bulletin, 140, 52–59.

20.Xin, L., Sun, X.*, & Lou, S.* (2016). Effects of methane-rich saline on the capability of one-time exhaustive exercise in male SD rats. PloS One, 11(3), e0150925.

21.Cai, M., Wang, H., Li, J. J., Zhang, Y. L., Xin, L., Li, F., & Lou, S.* (2016). The signaling mechanisms of hippocampal endoplasmic reticulum stress affecting neuronal plasticity-related protein levels in high fat diet-induced obese rats and the regulation of aerobic exercise. Brain, Behavior, and Immunity, 57, 347–359.